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Year 2 Quiz on Regulating CA Secretion, created by gina_evans0312 on 09/02/2014.

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Regulating CA Secretion

Question 1 of 18

1

What stimulates the secretion of the CA's?

Select one of the following:

  • An action potential

  • An increase in Noradrenaline

  • Nerve damage

Explanation

Question 2 of 18

1

Once the membrane has been depolarised, what voltage gated channels open?

Select one of the following:

  • Sodium

  • Calcium

  • Potassium

Explanation

Question 3 of 18

1

The influx of ions into the cell signals secretion by exocytosis

Select one of the following:

  • True
  • False

Explanation

Question 4 of 18

1

What is stored in Catecholamine vesicles, along with the CA?

Select one or more of the following:

  • ATP

  • ADP

  • Fromogranin

  • Chromogranin

Explanation

Question 5 of 18

1

ATP is -ve at body pH, whilst CA's are +ve

Select one of the following:

  • True
  • False

Explanation

Question 6 of 18

1

Why are CA's stored with these other substances?

Select one or more of the following:

  • They keep the CA's out of solution

  • They keep the CA's in solution

  • Which helps prevent vesicle lysis due to osmotic pressure

Explanation

Question 7 of 18

1

ATP can also act as a neurotransmitter

Select one of the following:

  • True
  • False

Explanation

Question 8 of 18

1

When concentrations of CA in the synapse are low, Alpha2 Adrenergic receptors are activated,

Select one of the following:

  • True
  • False

Explanation

Question 9 of 18

1

B2 receptors _ adenylate cyclase, which _ the production of cAMP, which _ the influx of ions

Select one of the following:

  • Stimulates, increases, increases

  • Stimulates, increases, decreases

  • Inhibits, increases, increases

  • Inhibits, decreases, decreases

Explanation

Question 10 of 18

1

A2 adrenergic receptors have the opposite effect of B2 adrenergic receptors

Select one of the following:

  • True
  • False

Explanation

Question 11 of 18

1

Re-uptake Method 1 is presynaptic, and mediated by what?

Select one or more of the following:

  • Active transport

  • Diffusion

  • A Na+/K+ pump

  • Na+ channel

Explanation

Question 12 of 18

1

Uptake Method 2 is extraneuronal and is used to...

Select one of the following:

  • Destroy excess adrenaline

  • Secrete adrenaline into the bloodstream

  • Stimulate separate neurones

Explanation

Question 13 of 18

1

Monoamine oxidase is found in the RER and interacts with cytoplasmic neurotransmitter

Select one of the following:

  • True
  • False

Explanation

Question 14 of 18

1

What is the role of monoamine oxidase (3 steps)?

Select one or more of the following:

  • Converts the amine --> aldehyde

  • Reduction of Aldehyde --> Acid

  • Reduction of Aldehyde --> Alcohol

Explanation

Question 15 of 18

1

Which enzyme uses S-Adenosty Methionine to methylate Neurotransmitters?

Select one of the following:

  • Monoamine Oxidase

  • Catcheol-O-Methyl Transferase

  • Catecholamine Methylase

Explanation

Question 16 of 18

1

What is the final produce of the Oxidative pathway of Monoamine Oxidase?

Select one of the following:

  • VMA

  • MOPEG

Explanation

Question 17 of 18

1

What is the final produce of the Reductive pathway of Monoamine Oxidase?

Select one of the following:

  • VMA

  • MOPEG

Explanation

Question 18 of 18

1

In peripheral tissue, the oxidative pathway predominates. In the brain, the reduction pathway predominates.

Select one of the following:

  • True
  • False

Explanation

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