Melissa Denker
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Undergraduate MBChB Year 2 Quiz on Endocrine Block - THYROID (Week 3), created by Melissa Denker on 30/11/2015.

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Melissa Denker
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Endocrine Block - THYROID (Week 3)

Question 1 of 10

1

Which connection allows communication between the hypothalamus and anterior pituitary gland?

Select one of the following:

  • Hypophyseal portal system

  • Hypothalamic hypophyseal tract

  • Infundibulum

  • Sphenoid sinus cavity surrounding the pituitary gland

Explanation

Question 2 of 10

1

Which connection allows communication between the hypothalamus and the posterior pituitary gland?

Select one of the following:

  • Hypophyseal portal system

  • Hypothalamic hypophyseal tract

  • Infundibulum

  • Sphenoid sinus cavity surrounding the pituitary gland

Explanation

Question 3 of 10

1

Which hormones are produced by the posterior pituitary gland?

Select one or more of the following:

  • Oxytocin

  • ADH

  • Prolactin

  • TSH

  • FSH/LH

  • GH

  • ACTH

Explanation

Question 4 of 10

1

What is the correct order of the following anterior pituitary cell types, from most abundant to least abundant?

Select one of the following:

  • Somatotrophs (50%)
    Lactotrophs (20%)
    Corticotrophs (10-15%)
    Gonadotrophs (10%)
    Thyrotrophs (5%)

  • Somatotrophs (50%)
    Lactotrophs (20%)
    Gonadotrophs (10-15%)
    Corticotrophs (10%)
    Thyrotrophs (5%)

  • Gonadotrophs (50%)
    Lactotrophs (20%)
    Corticotrophs (10-15%)
    Thyrotrophs (10%)
    Somatotrophs (5%)

  • Somatotrophs (50%)
    Lactotrophs (20%)
    Corticotrophs (10-15%)
    Thyrotrophs (10%)
    Gonadotrophs (5%)

  • Corticotrophs (50%)
    Lactotrophs (20%)
    Somatotrophs (10-15%)
    Gonadotrophs (10%)
    Thyrotrophs (5%)

Explanation

Question 5 of 10

1

What are the 6 hormones released by the anterior pituitary gland?

Select one or more of the following:

  • ADH

  • Oxytocin

  • GH

  • FSH/LH

  • Prolactin

  • ACTH

  • TSH

Explanation

Question 6 of 10

1

Which hypothalamic hormone stimulates the secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary gland?

Select one of the following:

  • Corticotrophic releasing hormone (CRH)

  • Thyroid releasing hormone (TRH)

  • Growth hormone releasing hormone (GHRH)

  • Gonadotrophin releasing hormone (GnRH)

  • Dopamine

Explanation

Question 7 of 10

1

Which test results would indicate cranial diabetes insipidus?

Select one of the following:

  • Water deprivation test - patients are desperate to drink; urine osmolality remains low
    Response to ADH - DI improves

  • Water deprivation test - patients are desperate to drink; urine osmolality stays low
    Response to ADH - DI does not improve

  • Water deprivation test - urine osmolality becomes high (i.e. concentrated)
    Response to ADH - DI improves

  • Water deprivation test - urine osmolality becomes high (i.e. becomes concentrated)
    Response to ADH - DI does not improve

Explanation

Question 8 of 10

1

What is the correct order for rates of functional pituitary adenomas?

Select one of the following:

  • Prolactinomas (30%)
    Cushing's disease (20%)
    Acromegaly (15%)
    TSHoma (<1%)

  • Prolactinomas (30%)
    Cushing's disease (20%)
    TSHomas (15%)
    Acromegaly (<1%)

  • Acromegaly (30%)
    Cushing's disease (20%)
    Prolactinomas (15%)
    TSHoma (<1%)

  • Prolactinomas (30%)
    TSHoma (20%)
    Acromegaly (15%)
    Cushing's disease (<1%)

Explanation

Question 9 of 10

1

Fill the blank spaces to complete the text.

Describe the process of thyroid hormone production:
1. Iodine is actively transported into the via on the basolateral side of the cell (this is called )
2. Iodine diffuses to the luminal side of the cell
3. Iodine is transported into the follicle lumen by , a membrane transporter
4. The follicle cells secrete (containing ~70 amino acids) into the lumen
5. Iodide ions undergo to form via the action of the enzyme
6. of the thyroglobulin molecule:
---Iodine binds to tyrosine amino acids within the thyroglobulin molecule via the action of
---This forms
---This undergoes further iodine binding to form
---MIT/DIT molecules are coupled to each other
7. If two DIT molecules couple together, is formed
8. If one MIT molecule couples with one DIT molecule, is formed

Explanation

Question 10 of 10

1

How much more concentrated is iodine in the thyroid than in the blood?

Select one of the following:

  • x30

  • x60

  • x90

  • x120

Explanation