Amber Agius
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This is a quiz on the classical pathway of the complement system

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Amber Agius
Created by Amber Agius about 2 years ago
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Classical Pathway

Classical Pathway

Question 1 of 16

1

Which one of these cleaves C4 into C4a and C4b?

Select one of the following:

  • C1s

  • C1q

  • C1r

Explanation

Question 2 of 16

1

Which antibody/antibodies can activate the classical pathway?

Select one or more of the following:

  • IgD

  • IgG

  • IgM

  • IgE

Explanation

Question 3 of 16

1

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( 1, 2, 3, 4, 5 ) pentameric ( IgM, IgD, IgG, IgE, IgA ) or ( 1, 2, 3, 4, 5 ) ( IgA, IgM, IgG, IgD, IgE ) ( in close proximity to each other, on opposite sides of the membrane, anywhere on the membrane ) are required to activate the classical pathway.

Explanation

Question 4 of 16

1

Fill the blank spaces to complete the text.

C3 convertase cleaves into and

Explanation

Question 5 of 16

1

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( C3b, C3a ) ( covalently attaches to, cleaves ) ( C3 convertase, C1q, C1r, C1s, C5 )

Explanation

Question 6 of 16

1

Fill the blank space to complete the text.

C5 convertase of the classical pathway is also known as

Explanation

Question 7 of 16

1

Fill the blank space to complete the text.

C5b initiates formation of

Explanation

Question 8 of 16

1

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MAC complex stands for ( Membrane, Microbial, Macrophage, Monocyte, Mast cell ) ( Attack, Acidosis, Amplification, Affinity, Antigen, Allotype ) Complex

Explanation

Question 9 of 16

1

MAC complex is initiated by C5a

Select one of the following:

  • True
  • False

Explanation

Question 10 of 16

1

MAC complex is initiated by C5b

Select one of the following:

  • True
  • False

Explanation

Question 11 of 16

1

The classical pathway pf the complement system is independent of antibody.

Select one of the following:

  • True
  • False

Explanation

Question 12 of 16

1

Fill the blank space to complete the text.

The C3 convertase of the classical pathway is also known as .

Explanation

Question 13 of 16

1

The C3 convertase of the classical pathway is C3bBb.

Select one of the following:

  • True
  • False

Explanation

Question 14 of 16

1

What does C3a do in the classical pathway of the complement system?

Select one of the following:

  • It opsonises microbial pathogens

  • It activates mast cells

  • It attaches covalently to C3 convertase

  • It attaches covalently to C5 convertase

Explanation

Question 15 of 16

1

What does C3b do in the classical pathway of the complement system?

Select one of the following:

  • It opsonises microbial pathogens

  • It activates mast cells

  • It attaches covalently to C3 convertase

  • It attaches covalently to C5 convertase

Explanation

Question 16 of 16

1

Fill the blank spaces to complete the text.

C2 binds to membrane bound , and is cleaved by into and . remains bound to C4b.

Explanation

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