Beth Moore
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undergraduate Microbiology Quiz on HIV and the immune system, created by Beth Moore on 29/05/2015.

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Beth Moore
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HIV and the immune system

Question 1 of 14

1

Which of the following does the HIV virus contain?

Select one or more of the following:

  • dsDNA

  • ssDNA

  • reverse transcriptase

  • ssRNA

Explanation

Question 2 of 14

1

What is the name of the viral receptor on the HIV virus envelope?

Select one of the following:

  • gp10

  • gp120

  • CD4

  • gp60

Explanation

Question 3 of 14

1

During which phase are a large number of virus particles produced?

Select one of the following:

  • Permissive

  • Lytic

  • Latent

Explanation

Question 4 of 14

1

Which of the following are thought to explain the CNS involvement with HIV?

Select one of the following:

  • Monocytes

  • Dentritic cells

  • Neutrophils

  • T-Helper cells

Explanation

Question 5 of 14

1

CD4 expression not sufficient for HIV infection

Select one of the following:

  • True
  • False

Explanation

Question 6 of 14

1

Approximately how long may it take for antibodies to the HIV virus to be produced?

Select one of the following:

  • 3-6 days

  • 3-6 months

  • 3-6 years

Explanation

Question 7 of 14

1

By which cells are the intially high levels of HIV virus cleared?

Select one of the following:

  • T-helper

  • T-cytotoxic

  • Neutrophils

  • NK cells

Explanation

Question 8 of 14

1

Approximately how long is the asymptomatic stage of the HIV infection?

Select one of the following:

  • 1-2 years

  • 5-8 years

  • 10-12 years

  • 15-20 years

Explanation

Question 9 of 14

1

At which point is the HIV infection officially called AIDS?

Select one of the following:

  • When T-helper levels are below 200 per mm^3

  • When T-helper levels are below 2000 per mm^3

  • When T-helper levels are below 1000 per mm^3

  • When T-helper levels are below 20 per mm^3

Explanation

Question 10 of 14

1

Which of the following is true of the HIV-1 virus?

Select one or more of the following:

  • Its origin is in west africa

  • Its origin is in central africa

  • The likely source is sooty mangabees

  • The likely source is chimpanzees

  • It is between 50-100 years old

  • It is the least viralent of the two strains

Explanation

Question 11 of 14

1

In which way is HIV most commonly transmitted?

Select one of the following:

  • Unprotected sex

  • IV drug use

  • Breast feeding

  • Mother-foetus

Explanation

Question 12 of 14

1

How high is the mutation rate of HIV compared to the flu?

Select one of the following:

  • 100x more

  • 10x more

  • 60x more

  • 20x more

Explanation

Question 13 of 14

1

How does Azidothymidine help protect against HIV?

Select one of the following:

  • It inhibits reverse transcriptase

  • It binds to gp120

  • Binds to provirus

Explanation

Question 14 of 14

1

Which of the following therapies is the current most effective against HIV?

Select one of the following:

  • Passive immunisation using monoclonal antibodies

  • Azidothymidine

  • Combination therapy

  • Gene editing

Explanation

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