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Gastro-Intestinal Disorders- Clinical Pharmacology 5th Year PMU

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Gastro-Intestinal Disorders- Clinical Pharmacology 5th Year PMU

Question 1 of 10

1

Which are the main drug groups for treatment of ulcer disease

Select one or more of the following:

  • antacids drugs

  • anti-secretion drugs

  • gastro-duodenal protectors

  • drugs against HP infections

Explanation

Question 2 of 10

1

Which are non-absorbent antacid drugs

Select one or more of the following:

  • sodium salts

  • calcium salts

  • aluminium salts

  • magnesium salts

Explanation

Question 3 of 10

1

Which are anti-secretion drugs

Select one or more of the following:

  • Proton pump inhibitors

  • H2-histamine blockers in stomach mucosa

  • M3-cholinergic blockers in stomach mucosa cells

  • COX inhibitors

Explanation

Question 4 of 10

1

Which drugs are used for eradication of Helicobacter pylori-infections

Select one or more of the following:

  • proton pump inhibitors

  • colloidal bismuthi salts

  • histamine blockers

  • antibacterial drugs

Explanation

Question 5 of 10

1

Proton pump inhibitors are

Select one or more of the following:

  • Omeprazole

  • Rabeprazole

  • Mizoprostol

  • Lansoprazole

Explanation

Question 6 of 10

1

Gastrointestinal mucosa protectors are

Select one or more of the following:

  • Sucralphate

  • Misoprostol

  • Probiotics

  • Colloidal bismuths salts

Explanation

Question 7 of 10

1

Well known drug interactions of proton pump inhibitors are

Select one or more of the following:

  • decreased absorption of some antibiotics as tetracyclines, isoniazid, ciprofloxacin

  • decreased absorption of some other drugs as digoxin, quinidine, theophylline, NSAIDs, warfarin

  • increased absorption of some antibiotics as tetracyclines, isoniazid, ciprofloxacin

  • increased absorption of other drugs as digoxin, quinidine, theophylline, warfarin

Explanation

Question 8 of 10

1

Drugs contraindicated during pregnancy or breast feedings are

Select one or more of the following:

  • Bismuth salts

  • Misoprostol

  • Proton pump inhibitors

  • Antacid drugs

Explanation

Question 9 of 10

1

Maintenance therapy is indicated for patients with

Select one or more of the following:

  • complicated chronic ulcer disease with bleeding and perforations

  • concomitant erosive reflux esophagitis or reflux gastritis

  • patients over 50 years of age and concomitant diseases requiring often usage of NSAIDs or other drugs irritating stomach or duodenal mucosa

  • chronic tobacco smokers or people with liver cirrhosis, chronic obstructive lung disease etc.

Explanation

Question 10 of 10

1

Corrections of dose regimen are recommended for

Select one or more of the following:

  • H2-histamine blockers treatment (Cimetidine or Ranitidine) for patients with liver insufficiency

  • H2-histamine blockers in patients with kidney insufficiency

  • Proton pump inhibitors in patients with liver insufficiency due to prolonged half-life

  • Proton pump inhibitors in patients with kidney insufficiency

Explanation

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