Emily Doyle
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Pathophysiology: The Biologic Basis of Disease in Adults and Children 8th Edition

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Emily Doyle
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Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Question 1 of 31

1

Why are infants most susceptible to significant losses in total body water?

Select one of the following:

  • High body surface-to-body size ratio

  • Slow metabolic rate

  • Kidneys are not mature enough to counter fluid losses

  • Inability to communicate adequately when he or she is thirsty

Explanation

Question 2 of 31

1

Why does obesity create a greater risk for dehydration in people?

Select one of the following:

  • Adipose cells contain little water because fat is water repelling.

  • The metabolic rate of obese adults is slower than the rate of lean adults.

  • The rate of urine output of obese adults is higher than in lean adults.

  • The thirst receptors of the hypothalamus do not function effectively.

Explanation

Question 3 of 31

1

A patient’s blood gases reveal the following findings: pH 7.3; bicarbonate (HCO3) 27 mEq/L;
carbon dioxide (CO2) 58 mm Hg. What is the interpretation of these gases?

Select one of the following:

  • Respiratory alkalosis

  • Metabolic acidosis

  • Respiratory acidosis

  • Metabolic alkalosis

Explanation

Question 4 of 31

1

Water movement between the intracellular fluid (ICF) compartment and the extracellular fluid
(ECF) compartment is primarily a function of what?

Select one of the following:

  • Osmotic forces

  • Plasma oncotic pressure

  • Antidiuretic hormone

  • Hydrostatic forces

Explanation

Question 5 of 31

1

In addition to osmosis, what force is involved in the movement of water between the plasma
and interstitial fluid spaces?

Select one of the following:

  • Oncotic pressure

  • Buffering

  • Net filtration

  • Hydrostatic pressure

Explanation

Question 6 of 31

1

Venous obstruction is a cause of edema because of an increase in which pressure?

Select one of the following:

  • Capillary hydrostatic

  • Interstitial hydrostatic

  • Capillary oncotic

  • Interstitial oncotic

Explanation

Question 7 of 31

1

At the arterial end of capillaries, why does fluid move from the intravascular space into the
interstitial space?

Select one of the following:

  • Interstitial hydrostatic pressure is higher than the capillary hydrostatic pressure.

  • Capillary hydrostatic pressure is higher than the capillary oncotic pressure.

  • Interstitial oncotic pressure is higher than the interstitial hydrostatic pressure.

  • Capillary oncotic pressure is lower than the interstitial hydrostatic pressure.

Explanation

Question 8 of 31

1

Low plasma albumin causes edema as a result of a reduction in which pressure?

Select one of the following:

  • Capillary hydrostatic

  • Interstitial hydrostatic

  • Plasma oncotic

  • Interstitial oncotic

Explanation

Question 9 of 31

1

How are secretion of antidiuretic hormone (ADH) and the perception of thirst stimulated?

Select one of the following:

  • Decrease in serum sodium

  • Increase in plasma osmolality

  • Increase in glomerular filtration rate

  • Decrease in osmoreceptor stimulation

Explanation

Question 10 of 31

1

Thirst activates osmoreceptors following an increase in which blood plasma component?

Select one of the following:

  • Antidiuretic hormone

  • Aldosterone

  • Hydrostatic pressure

  • Osmotic pressure

Explanation

Question 11 of 31

1

A student asks about natriuretic peptides. Which statement by the professor is most accurate?

Select one of the following:

  • Decrease blood pressure and increase sodium and water excretion.

  • Increase blood pressure and decrease sodium and water excretion.

  • Increase heart rate and decrease potassium excretion.

  • Decrease heart rate and increase potassium excretion.

Explanation

Question 12 of 31

1

When changes in total body water are accompanied by proportional changes in electrolytes,
what type of alteration occurs?

Select one of the following:

  • Isotonic

  • Hypertonic

  • Hypotonic

  • Normotonic

Explanation

Question 13 of 31

1

Which enzyme is secreted by the juxtaglomerular cells of the kidney when circulating blood
volume is reduced?

Select one of the following:

  • Angiotensin I

  • Angiotensin II

  • Aldosterone

  • Renin

Explanation

Question 14 of 31

1

A patient in the hospital has hypernatremia. What condition should the healthcare professional
assess for?

Select one of the following:

  • Syndrome of inappropriate antidiuretic hormone

  • Hypersecretion of aldosterone

  • Brief bouts of vomiting or diarrhea

  • Excessive diuretic therapy

Explanation

Question 15 of 31

1

A patient has a serum sodium level of 165 mEq/L. The healthcare professional explains that
the clinical manifestations of confusion, convulsions, cerebral hemorrhage, and coma are
caused by what mechanism?

Select one of the following:

  • High sodium in the blood vessels pulls water out of the brain cells into the blood vessels, causing brain cells to shrink.

  • High sodium in the brain cells pulls water out of the blood vessels into the brain cells, causing them to swell.

  • Low sodium in the blood vessels pulls potassium out of the brain cells, which
    slows the synapses in the brain.

  • Low sodium in the blood vessels draws chloride into the brain cells followed by
    water, causing the brain cells to swell.

Explanation

Question 16 of 31

1

What does vomiting-induced metabolic alkalosis cause?

Select one of the following:

  • Retained sodium to bind with the chloride

  • Hydrogen to move into the cell and exchange with potassium

  • Retention of bicarbonate to maintain the anion balance

  • Hypoventilation to compensate for the metabolic alkalosis

Explanation

Question 17 of 31

1

The pathophysiologic process of edema is related to which mechanism?

Select one of the following:

  • Sodium depletion

  • Decreased capillary hydrostatic pressure

  • Increased plasma oncotic pressure

  • Lymphatic obstruction

Explanation

Question 18 of 31

1

Why is insulin used to treat hyperkalemia?

Select one of the following:

  • Stimulates sodium to be removed from the cell in exchange for potassium

  • Binds to potassium to remove it through the kidneys

  • Transports potassium from the blood into the cell along with glucose

  • Breaks down the chemical components of potassium, inactivating it

Explanation

Question 19 of 31

1

A major determinant of the resting membrane potential necessary for the transmission of
nerve impulses is the ratio between what?

Select one of the following:

  • Intracellular and extracellular Na+

  • Intracellular and extracellular K+

  • Intracellular Na+ and extracellular K+

  • Intracellular K+ and extracellular Na+

Explanation

Question 20 of 31

1

During acidosis, the body compensates for the increase in serum hydrogen ions by shifting
hydrogen ions into the cell in exchange for which electrolyte?

Select one of the following:

  • Oxygen

  • Sodium

  • Potassium

  • Magnesium

Explanation

Question 21 of 31

1

A healthcare professional is caring for four patients. Which patient should the professional
assess for hyperkalemia?

Select one of the following:

  • Hyperparathyroidism

  • Vomiting

  • Renal failure

  • Hyperaldosteronism

Explanation

Question 22 of 31

1

In hyperkalemia, what change occurs to the cells’ resting membrane potential?

Select one of the following:

  • Hypopolarization

  • Hyperexcitability

  • Depolarization

  • Repolarization

Explanation

Question 23 of 31

1

A patient’s chart indicates Kussmaul respirations. The student asks the healthcare professional
what this is caused by. What response by the professional is most accurate?

Select one of the following:

  • Anxiety leads to Kussmaul respirations and is a cause of respiratory acidosis.

  • A compensatory measure is needed to correct metabolic acidosis.

  • Diabetic ketoacidosis is leading to metabolic acidosis

  • More oxygen is necessary to compensate for respiratory acidosis.

Explanation

Question 24 of 31

1

A healthcare provider notes that tapping the patient’s facial nerve leads to lip twitching. What
electrolyte value is correlated with this finding?

Select one of the following:

  • K+: 2.8 mEq/L

  • K+: 5.4 mEq/L

  • Ca++: 8.2 mg/dL

  • Ca++: 12.9 mg/dL

Explanation

Question 25 of 31

1

A patient has a history of excessive use of magnesium-containing antacids and
aluminum-containing antacids. What lab value does the healthcare professional correlate to
this behavior?

Select one of the following:

  • Magnesium 1.8 mg/dL

  • Phosphate 1.9 mg/dL

  • Sodium 149 mEq/L

  • Potassium 2.5 mEq/L

Explanation

Question 26 of 31

1

A healthcare professional is caring for four patients. Which patient should the professional
assess for hypermagnesemia as a priority?

Select one of the following:

  • Hepatitis

  • Renal failure

  • Trauma to the hypothalamus

  • Pancreatitis

Explanation

Question 27 of 31

1

Physiologic pH is maintained at approximately 7.4 because bicarbonate (HCO3) and carbonic
acid (H2CO3) exist in what ratio?

Select one of the following:

  • 20:1

  • 1:20

  • 10:2

  • 10:5

Explanation

Question 28 of 31

1

Where is two thirds of the body’s water found?

Select one of the following:

  • Interstitial fluid spaces

  • Vascular system

  • Intracellular fluid compartments

  • Intraocular fluids

Explanation

Question 29 of 31

1

A healthcare professional just administered a large dose of insulin to a patient. Which
electrolyte value should the professional monitor as a priority?

Select one of the following:

  • Sodium

  • Potassium

  • Calcium

  • Magnesium

Explanation

Question 30 of 31

1

Why does increased capillary hydrostatic pressure result in edema?

Select one of the following:

  • Losses or diminished production of plasma albumin

  • Inflammation resulting from an immune response

  • Blockage within the lymphatic channel system

  • Sodium and water retention

Explanation

Question 31 of 31

1

A patient’s electrocardiogram (ECG) shows tall, peaked T waves. What lab value or
assessment would the healthcare professional correlate with this finding?

Select one of the following:

  • Positive Chvostek sign

  • Serum potassium 6.7 mEq/L

  • Nausea and vomiting

  • Serum sodium 138 mEq/L

Explanation