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Quiz on Contol of Gene Expression , created by MPusey on 05/01/2015.

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Contol of Gene Expression

Question 1 of 20

1

All cells have the same genes. True or false?

Select one of the following:

  • True
  • False

Explanation

Question 2 of 20

1

Which of these are examples of house-keeping genes?

Select one or more of the following:

  • Glycolysis enzymes

  • DNA polymerase

  • Genes that code for haemoglobin

  • Genes that code for melanin

  • Genes that code for the cytoskeleton

Explanation

Question 3 of 20

1

What are the types of transcript?

Select one or more of the following:

  • Abundant transcript

  • Rare transcript

  • No transcript

  • Positive transcript

  • Negative transcript

Explanation

Question 4 of 20

1

To what level are house-keeping genes normally transcribed?

Select one of the following:

  • Abundant transcript

  • Rare transcript

  • No transcript

Explanation

Question 5 of 20

1

When might genes that usually have no transcript be transcribed?

Select one or more of the following:

  • During development

  • In response to a stimuli

  • In disease states

Explanation

Question 6 of 20

1

The amount that genes are transcribed cannot be altered. True or false?

Select one of the following:

  • True
  • False

Explanation

Question 7 of 20

1

What are transcription factors?

Select one of the following:

  • Proteins that bind to DNA to prevent or allow transcription to occur

  • Proteins that bind to DNA and unwind it initiating transcription

  • Proteins that bind to RNA polymerase making it more efficient

Explanation

Question 8 of 20

1

What two transcription factors are present in the Lac Operon?

Select one or more of the following:

  • CAP Protein

  • Lac represser

  • Lac ZYA

  • TATA proteins

Explanation

Question 9 of 20

1

Where do transcription factors bind to in eukaryotes?

Select one of the following:

  • The major groove in DNA

  • The minor groove in DNA

  • The promoter

  • The telomere

Explanation

Question 10 of 20

1

Why do transcription factors bind to the major groove?

Select one or more of the following:

  • The base pairs are not exposed in the minor groove

  • There are more binding sites in the major groove

  • The major groove is more recognizable

  • There is not enough room in the minor groove

Explanation

Question 11 of 20

1

Transcription factors have to unwind DNA to find their binding point. True or false?

Select one of the following:

  • True
  • False

Explanation

Question 12 of 20

1

What are TATA boxes?

Select one of the following:

  • A part of DNA made up of many thymines and adenines which act as a binding site for transcription factors

  • An area of DNA where thymine and adenine alternate for more then 100 base pairs to signal the end of an intron

  • An area of DNA where thymines and adenines are added gradually throughout life that scientists use to estimate the age of someone

Explanation

Question 13 of 20

1

What transcription factor binds to TATA boxes?

Select one of the following:

  • TBP

  • Lac ZYA

  • CAP protein

Explanation

Question 14 of 20

1

What are regulatory elements?

Select one of the following:

  • Specific patterns that are recognized by regulatory factors

  • Generic patterns that are recognized by a variety of regulatory factors

  • Palindromic patterns in DNA that are recognized by regulatory factors

Explanation

Question 15 of 20

1

In eukaryotes, often it requires many transcription factors to lead to transcription. True or false?

Select one of the following:

  • True
  • False

Explanation

Question 16 of 20

1

Are histones positively or negatively charged?

Select one of the following:

  • Positively

  • Negatively

Explanation

Question 17 of 20

1

Why do histones need to positively charged?

Select one of the following:

  • So they can bind to DNA

  • So they can move through the nuclear membrane

  • So they can move through the cell membrane

  • So they don't interact with protein synthesis

Explanation

Question 18 of 20

1

How do transcription factors make histones disassociate from DNA?

Select one of the following:

  • They acetylate them so there is no positive charge

  • They give DNA in that area a neutral charge so the histones can no longer bind to it

  • They add chloride ions to the histones to make them negatively charged

Explanation

Question 19 of 20

1

Why is it necessary to disassociate the histones from DNA?

Select one of the following:

  • So that transcription can occur

  • So DNA can be replicated

  • So that DNA can coil up tight enough to fit within the nucleus of the cell

  • To allow DNA to be studied under a microscope

  • To allow DNA to form its double helix shape

Explanation

Question 20 of 20

1

The less differentiated a cell is the more likely it is able to go back to its undifferentiated state. True or false?

Select one of the following:

  • True
  • False

Explanation