skhal
Quiz by , created more than 1 year ago

A compilation of all of the quizzes from lecture on relevant topics for the final. I forgot to write down the quizzes for topics 25 and 26 though so those are missing.

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skhal
Created by skhal almost 10 years ago
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Lecture quizzes

Lecture quizzes

Question 1 of 21

1

Which property is not essential for the origin of life?

Select one of the following:

  • The need to store information

  • The need to duplicate information

  • The need to change information

  • The need to make proteins

  • The need to convert into favorable reactions

Explanation

Question 2 of 21

1

Why is it thought that ribozymes are likely to be a legacy from an ancestral RNA world?

Select one of the following:

  • They are more stable than RNAs

  • When they act, they require the presence of protein cofactors

  • They act without the participation of protein cofactors.

  • They can be made spontaneously without a DNA template.

  • They are made by proteins

Explanation

Question 3 of 21

1

What was probably the first carrier of genetic information in primitive organisms?

Select one of the following:

  • DNA that could self-replicate

  • Proteins

  • Polypeptides

  • RNA that could self-replicate

  • Lipids

Explanation

Question 4 of 21

1

________ can be used to purify transcription activator proteins

Select one of the following:

  • Gel mobility shift assays

  • DNA affinity chromatography

  • Centrifugation

  • DNA footprinting

  • ChIP assays

Explanation

Question 5 of 21

1

Sequence specific DNA binding proteins frequently have a region that binds in the major groove because:

Select one of the following:

  • It is smaller

  • It contains sequence specific information

  • The minor groove is not available

  • It is positively charged

  • It is negatively charged

Explanation

Question 6 of 21

1

The following secondary structures are known to specifically interact with DNA (select all that apply):

Select one or more of the following:

  • Alpha helix

  • Beta sheet

  • Unstructured loops

  • Double helix

Explanation

Question 7 of 21

1

What happens at the lac operon in the absence of glucose and presence of lactose?

Select one of the following:

  • No expression

  • Low expression

  • The lac repressor binds the promoter

  • High expression

  • The CAP protein doesn't bind to the promoter

Explanation

Question 8 of 21

1

Multiple binding sites for a repressor is advantageous because:

Select one of the following:

  • There are too many repressors in cells

  • DNA must be bent to allow transcription

  • Repressors are only active when bound to many sites at once

  • This increases the effective concentration of the repressor

  • Repressors need multiple binding sites to bind ligands

Explanation

Question 9 of 21

1

An operator is:

Select one of the following:

  • A protein

  • A protein binding site

  • The same as a promoter

  • A type of repressor

  • The start site for RNA synthesis

Explanation

Question 10 of 21

1

Mammalian x-chromosome inactivation:

Select one of the following:

  • Occurs only in humans

  • Prevents females from being mosaics

  • Is not necessary

  • Is necessary for dosage compensation

  • Only occurs in males

Explanation

Question 11 of 21

1

CpG islands are generally found in

Select one of the following:

  • Inactive genes

  • Introns

  • Exons

  • Promoters of constantly active genes

  • Promoters of rarely expressed genes

Explanation

Question 12 of 21

1

Deamination of methyl-cytosine:

Select one of the following:

  • Does not occur

  • Changes methyl-cytosine to thymine

  • Only occurs in the sequence CG

  • Results in genomic imprinting

  • Occurs only in expressed genes

Explanation

Question 13 of 21

1

Sex determination in drosophila is due to:

Select one of the following:

  • Riboswitches

  • Alternative splicing

  • Alternative 3' end cleavage

  • Localization of mRNA

  • Alternative translational initiation

Explanation

Question 14 of 21

1

Mirco RNAs (miRNAs):

Select one of the following:

  • Are the same as rRNAs

  • Are not encoded by the genome

  • Are found only in bacteria

  • Are involved in gene repression

  • Are part of ribosomes

Explanation

Question 15 of 21

1

Attenuation involves regulation of:

Select one of the following:

  • Translation

  • Replication

  • Recombination

  • Transcription

  • Proteolysis

Explanation

Question 16 of 21

1

Ion exchange chromatography separates:

Select one of the following:

  • Proteins, based on size

  • Proteins, based on surface charge

  • Proteins, based on source

Explanation

Question 17 of 21

1

FRET is used to study:

Select one of the following:

  • Protein structure

  • Protein molecular weight

  • Protein/protein interaction

  • Protein sequence

  • Protein denaturation

Explanation

Question 18 of 21

1

SDS is used in protein gels to (select all that apply)...

Select one or more of the following:

  • Make glassware clean up easier

  • Help denature proteins

  • To create a uniform mass/charge ratio

  • To reduce disulfide bonds

Explanation

Question 19 of 21

1

DNA libraries are used to bank (select all that apply):

Select one or more of the following:

  • Genomic DNA

  • RNA

  • cDNA

  • Artificial chromosomes

Explanation

Question 20 of 21

1

Dideoxy nucleotides are used in DNA sequences to:

Select one of the following:

  • Denature the DNA

  • Hybridize the DNA

  • Chain terminate the DNA

  • Elongate the DNA

  • Transcribe the DNA

Explanation

Question 21 of 21

1

Hybridization of nucleic acids refers to:

Select one of the following:

  • A renaturation technique

  • An electrophoretic technique

  • A cloning technique

  • A forensic technique

  • A purification technique

Explanation

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