Mer Scott
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PHCY310 Quiz on L34.5 CKD and AKI, created by Mer Scott on 16/04/2019.

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Mer Scott
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L34.5 CKD and AKI

Question 1 of 7

1

Choose the incorrect statement about Acute Kidney Injury (AKI).

Select one of the following:

  • It is an abrupt decrease in kidney function that occurs over a period of 7 days or less

  • It is stimated to occur in approximately 50% of patients admitted to the intensive care unit (ICU)

  • It can predispose you to CKD

  • CKD patients cannot get AKI

Explanation

Question 2 of 7

1

Choose the incorrect statement about chronic kidney disease (CKD)

Select one of the following:

  • It is abnormalities in kidney structure or function that persist for >90 days

  • It presents a high economic burden

  • At least as many deaths are attributable to kidney disease as to cancer, diabetes or respiratory diseases

  • Risk factors for AKI and CKD, such as advanced age, diabetes and hypertension, often overlap.

  • AKI and CKD are discrete and separate conditions.

Explanation

Question 3 of 7

1

NZ has higher rates of sepsis, post infectious glomerulonephritis and HUS causing AKI compared with other countries in the developed world.

Select one of the following:

  • True
  • False

Explanation

Question 4 of 7

1

Reduced renal blood flow () initiates AKI. It can be as a result of infection (), medications, disease, or trauma. The medication combination likely to cause AKI is the ‘triple whammy’; concurrent use of an inhibitor or an ARB, with a .
AKI is largely and late diagnosis of injury is common.

Select option below to complete the highlighted text

    ischemia
    sepsis
    diuretic and an NSAID
    ACE
    asymptomatic

Explanation

Question 5 of 7

1

Pathogenesis of AKI:
1. Disruptions of the glycocalyx and monolayer in renal tubule
2. Upregulation of molecules
3. Enhanced interactions
4. Formation of
5. Inflammation causing overload, imbalances

Select option below to complete the highlighted text

    endothelial
    adhesion
    leukocyte-endothelium
    microthrombi
    fluid
    electrolyte

Explanation

Question 6 of 7

1

CKD Pathogenesis"
1. Nephrons atrophy with time
2. Worsened by genetic & environmental factors –
3. Fewer nephrons cause an increase in size, can’t cope & detach – loss of barrier function and impaired filtration -
4. Inflammation, which leads to fibrosis & formation
5. Leads to

Select option below to complete the highlighted text

    hypertrophy
    nephron
    podocytes
    proteinuria
    scar
    ischaemia

Explanation

Question 7 of 7

1

Which of these is not a systemic effect of CKD?

Select one of the following:

  • Fluid & electrolyte imbalances

  • Anaemia

  • Mineral bone disorder – bone pain, fractures, deformities

  • Metabolic acidosis – muscle wasting, bone demineralisation

  • Hyperuricaemia – systemic inflammation, neurological changes

  • Pruritis

Explanation

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