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Adrenegic Drugs- Pharmacology 4th Year- PMU

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Adrenegic Drugs- Pharmacology 4th Year- PMU

Question 1 of 31

1

According to their mechanism of action the adrenergic agonists can be divided in:

Select one or more of the following:

direct agonists
indirect agonists
agonists with mixed mechanism of action
natural compounds

Explanation

Question 2 of 31

1

α1-adrenoceptors are located on:

Select one or more of the following:

presynaptic neuronal endings
postsynaptic neuronal endings
blood vessels
iris dilator muscle

Explanation

Question 3 of 31

1

β1-adrenoceptors are located on:

Select one or more of the following:

postsynaptic neuronal endings
presynaptic neuronal endings
myocardial cells
juxtaglomerular apparatus in the kidney

Explanation

Question 4 of 31

1

β2-adrenoceptors are located on:

Select one or more of the following:

postsynaptic neuronal endings
bronchial smooth muscles
liver
uterus (womb)

Explanation

Question 5 of 31

1

β3-adrenoceptors are located in:

Select one or more of the following:

adipose tissue
urinary bladder
presynaptic neuronal endings
bronchial smooth muscles

Explanation

Question 6 of 31

1

Pharmacological effects of Epinephrine are:

Select one or more of the following:

positive chronotropic effect
blood pressure elevation
bronchial smooth muscles dilation
elevated levels of blood sugar

Explanation

Question 7 of 31

1

Indications for the clinical use of Epinephrine are:

Select one or more of the following:

anaphylactic shock
hypoglycaemia
arrhythmia
glaucoma with wide iridocorneal angle

Explanation

Question 8 of 31

1

Potential adverse drug reactions of Epinephrine are:

Select one or more of the following:

hypoglycaemia
arrhythmia
tremor
anxiety and restlessness

Explanation

Question 9 of 31

1

Clinical indications for prescribing α1-agonists are:

Select one or more of the following:

arterial hypotension
acute rhinitis
asthma attack
heart block

Explanation

Question 10 of 31

1

Pharmacological effects of the selective β2-agonists are:

Select one or more of the following:

pupillary dilation
bronchial dilation
blood pressure elevation
relaxation of uterine muscle

Explanation

Question 11 of 31

1

Which of the following drugs are selective β2-agonists?

Select one or more of the following:

lsoprenalini sulfas
Orciprenalini sulfas
Salbutamol
Salmeterol

Explanation

Question 12 of 31

1

β2-agonists are indicated in:

Select one or more of the following:

bronchial asthma
digitalis intoxication
arterial hypertension
threatening abortion

Explanation

Question 13 of 31

1

Adverse drug reactions of β2-agonists are:

Select one or more of the following:

finger tremor
bronchial dilatation
hyperglycemia
tolerance

Explanation

Question 14 of 31

1

What are the main features of the indirect-acting adrenergic agonists?

Select one or more of the following:

stimulation of central nervous system
drug tolerance and dependence
have no effect on the cardio-vascular system
used for treatment of narcolepsy and attention deficiency hyperactivity disorder (ADHD)

Explanation

Question 15 of 31

1

Clinically desirable interactions can occur between β2-agonists and:(find correct answer)

Select one or more of the following:

tricyclic antidepressants
inhaled corticosteroids
inhaled antimuscarinic drugs
beta blockers

Explanation

Question 16 of 31

1

Mechanisms of action of the presynaptic adrenolytics are:

Select one or more of the following:

blockade of the presynaptic α2-receptors
activation of the presynaptic α2-receptors
conversion to a “false“ neurotransmitter
blockade of the phosphodiesterase enzyme

Explanation

Question 17 of 31

1

Which of the following drugs act as agonists of the presynaptic α2-adrenoceptors?

Select one or more of the following:

Salbutamol
Clonidini hydrochloridum
α-Methyldopum (Dopegyt)
Sotalol

Explanation

Question 18 of 31

1

Pharmacological effects of Clonidin are:

Select one or more of the following:

decreased peripheral vascular resistance
antihypertensive
inhibition of gastric secretion
antiarrhythmic

Explanation

Question 19 of 31

1

Adverse drug reactions of Clonidin are:

Select one or more of the following:

Dry mouth
Drowsiness and depression
Hypertensive attacks following abrupt cessation of treatment
CNS stimulation

Explanation

Question 20 of 31

1

For Methyldopa is true:

Select one or more of the following:

has antihypertensive effect
it is safe in pregnancy
could cause drug-induced parkinsonism
used to treat threatening abortion

Explanation

Question 21 of 31

1

Which of the following drugs are α1-adrenoblockers?

Select one or more of the following:

Prazosin
Doxazosin
Clonidin
Chlorpromazin

Explanation

Question 22 of 31

1

Pharmacological effects of Prazosin are:

Select one or more of the following:

dilation of the resistive and capacitive vessels
antihypertensive
relaxation of the muscles in the prostate and bladder neck
hyperglycaemia

Explanation

Question 23 of 31

1

Adverse drug reactions of α1-adrenoblockers are:

Select one or more of the following:

orthostatic collapse
hypokalemia
fluid retention
hypoglycaemia

Explanation

Question 24 of 31

1

Which of the following drugs are non-selective β-blockers?

Select one or more of the following:

Atenolol
Pindolol
Acebutolol
Propranolol

Explanation

Question 25 of 31

1

Which of the following drugs are selective β1-blockers?

Select one or more of the following:

Atenolol
Pindolol
Propranolol
Metoprolol

Explanation

Question 26 of 31

1

β-blockers are indicated in case of:

Select one or more of the following:

hypertension
bronchial asthma
arrhythmia
ischaemic heart disease

Explanation

Question 27 of 31

1

Pharmacological effects of B-blockers are:

Select one or more of the following:

bronchodilation
negative inotropic effect
positive chronotropic effect
negative chronotropic effect

Explanation

Question 28 of 31

1

β-blocker approved for topical use in treatment of glaucoma is:

Select one or more of the following:

Bisoprolol
Metoprolol
Timolol
Propranolol

Explanation

Question 29 of 31

1

When applied topically in the eye the B-blocker Timolol will:

Select one or more of the following:

increase the intraocular pressure
decrease the intraocular pressure
cause miosis
cause mydriasis

Explanation

Question 30 of 31

1

Potential adverse drug reactions of β-blockers are.

Select one or more of the following:

hypoglycaemia
bronchoconstriction
hyperglycaemia
nightmares

Explanation

Question 31 of 31

1

For long-term treatment with β-blockers is true:

Select one or more of the following:

up-regulation of B-adrenergic receptors
down-regulation of B-adrenergic receptors
the therapy should be ceased abruptly
the therapy should not be ceased abruptly

Explanation