Healing in specalised tissues

Question 1 of 27

1

Granulation tissue appearance includes ❌ from venular endothelium
--> perpendicular to the wound surface, leaky (❌, ❌ (protein rich).
--> ❌ growing in from sides and base of wound: makes collagen type 3 then 1, change phenotye to ❌ ( wound ❌ ), hyaluronic acid and sulfated proteoglycans made.

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capillary sprouts

oedema

exudate

Fibroblasts

myofibroblast

contraction

Explanation

Question 2 of 27

1

Bone fracture is a bone lesion which leads to bone discontinuity

Select one of the following:

True
False

Explanation

Question 3 of 27

1

Bone repair depends on;
Type of ❌ - Result of strength & direction of applied force --> ❌ force (compressional fracture), Torsion force (❌ fracture), Combined ❌ and compressional force leads to an ❌ and displaced fracture
Adjacent tissue damage effects ❌ of repair. (e.g muscles)

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break

axial

spiral

torsion

angled

rate

growth

deterioration

Explanation

Question 4 of 27

1

which one of these are bone repair host factors?

Select one or more of the following:

Age, nutrition & overall health
Site of injury
immobilisation of fracture
degree of damage

Explanation

Question 5 of 27

1

healing of bone is triphasic

Select one of the following:

True
False

Explanation

Question 6 of 27

1

Fill the blank spaces to complete the text.

Healing of bone phases
1:
2: Reparative
3:

Explanation

Question 7 of 27

1

What would most likely to occur after 2 days of bone injury?

Select one or more of the following:

Blood clot formation
Ingrowth of capillary sprouts & fibroblasts from wound edge
Fibrocartilage formation
trabeculae of cancellous bone unite

Explanation

Question 8 of 27

1

Callus formation into chondrocytes is in remodelling phase of bone repair.

Select one of the following:

True
False

Explanation

Question 9 of 27

1

Fill the blank space to complete the text.

Bone Callus is a collar of cells around a bone fracture. Has the same function as granulation tissue.

Explanation

Question 10 of 27

1

In the reparative phase (II) of bone repair, Trabeculae of ❌ bone slowly unite. There's ❌ ingrowth from edge of marrow cavity. ❌ differentiate, cancellous bone laid down. ❌ formed in less vascular areas. After long periods of time, ❌ start to remodel. Marrow slowly replaced.

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cancellous

dense

capillary

veins

Osteoblasts

chondroblasts

Fibrocartilage

Hyaline cartilage

osteoclasts

Explanation

Question 11 of 27

1

Select from the dropdown lists to complete the text.

In ( Remodelling, Inflammatory, Reparative ) phase (III) of bone repair, it may take years. Bone contours are re-organised and excess ( callus, scar tissue ) removed.

Explanation

Question 12 of 27

1

What happens after weeks of bone repair?

Select one or more of the following:

Chondrocytes multiply
All cancellous bone converted of to lamellar bone
Chondrocytes mineralises & dies after callus is vascularised
It is the remodelling phase, callus is removed

Explanation

Question 13 of 27

1

Fill the blank space to complete the text.

Surgical incisions in bone --> healing with minimal formation and minimal disruption to the bone's ordered structure

Explanation

Question 14 of 27

1

Neuronal cells are mitotic and can be replaced

Select one of the following:

True
False

Explanation

Question 15 of 27

1

What is Gliolisis?

Select one of the following:

Proliferation of neuroglia repairing damage
Glial cells dying off
Neurons proliferating
Dendrites proliferating

Explanation

Question 16 of 27

1

In PNS (Peripheral nervous system), nerve axons can be ❌. If Basement membrane of ❌ is disrupted, resorbed axons may miss each other resulting in a traumatic ❌. If they are ❌, axonal growth has path to follow.

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replaced

Schwann

myelin sheath

neuroma

neuroblastoma

carcinoma

intact

removed

Explanation

Question 17 of 27

1

When basement membrane is intact; (PNS)

Select one or more of the following:

Growth of axonal sprouts from surviving stumps begin at 4mm/day
There is no axonal sprout growth.
Myelin sheath breaks down around axonal tip

Explanation

Question 18 of 27

1

Tissue healing in liver - acute injury heals by complete regeneration, whilst chronic is usually leading to collapse of reticulin framework, along with surrounding by fibrosis also known as CIRRHOSIS.

Select one of the following:

True
False

Explanation

Question 19 of 27

1

Which one of these are correct in regards to tissue healing in kidneys?

Select one or more of the following:

Tubular epithelium can regenerate after damage
Glomeruli can regenerate - No scar tissue
Glomeruli cannot regenerate - Scar tissue formed

Explanation

Question 20 of 27

1

Metaplasia is a form of healing in epithelial surfaces

Select one of the following:

True
False

Explanation

Question 21 of 27

1

An example of metaplasia includes replacement of ciliated columnar epithelium to squamous type that is resistant to trauma in chronic smoking damaged individuals.

Select one of the following:

True
False

Explanation

Question 22 of 27

1

Cardiac muscle cells are permanent and does not regenerate. Repairs by fibrosis

Select one of the following:

True
False

Explanation

Question 23 of 27

1

Skeletal muscle has no ability of healing/regeneration at all.

Select one of the following:

True
False

Explanation

Question 24 of 27

1

Smooth muscle has limited regeneration - can regenerate if loss is minimal

Select one of the following:

True
False

Explanation

Question 25 of 27

1

Select from the dropdown lists to complete the text.

Respiratory epithelium ( can, cannot ) regenerate. However, basement membrane must be intact and CT framework minimally disrupted. If basement membrane disrupted, ( fibrosis, inflammation ) occurs.

	Created by Laura Currie about 6 years ago

Medicine Quiz on Healing in specalised tissues, created by Laura Currie on 27/10/2018.

Healing in specalised tissues

Healing in specalised tissues

Question 1 of 27

Drag and drop to complete the text.

Explanation

Question 2 of 27

Bone fracture is a bone lesion which leads to bone discontinuity

Select one of the following:

Explanation

Question 3 of 27

Bone repair depends on; Type of ❌ - Result of strength & direction of applied force --> ❌ force (compressional fracture), Torsion force (❌ fracture), Combined ❌ and compressional force leads to an ❌ and displaced fracture Adjacent tissue damage effects ❌ of repair. (e.g muscles)

Drag and drop to complete the text.

Explanation

Question 4 of 27

which one of these are bone repair host factors?

Select one or more of the following:

Explanation

Question 5 of 27

healing of bone is triphasic

Select one of the following:

Explanation

Question 6 of 27

Fill the blank spaces to complete the text.

Healing of bone phases 1: 2: Reparative 3:

Explanation

Question 7 of 27

What would most likely to occur after 2 days of bone injury?

Select one or more of the following:

Explanation

Question 8 of 27

Callus formation into chondrocytes is in remodelling phase of bone repair.

Select one of the following:

Explanation

Question 9 of 27

Fill the blank space to complete the text.

Bone Callus is a collar of cells around a bone fracture. Has the same function as granulation tissue.

Explanation

Question 10 of 27

In the reparative phase (II) of bone repair, Trabeculae of ❌ bone slowly unite. There's ❌ ingrowth from edge of marrow cavity. ❌ differentiate, cancellous bone laid down. ❌ formed in less vascular areas. After long periods of time, ❌ start to remodel. Marrow slowly replaced.

Drag and drop to complete the text.

Explanation

Question 11 of 27

Select from the dropdown lists to complete the text.

In Remodelling Inflammatory Reparative( Remodelling, Inflammatory, Reparative ) phase (III) of bone repair, it may take years. Bone contours are re-organised and excess callus scar tissue( callus, scar tissue ) removed.

Explanation

Question 12 of 27

What happens after weeks of bone repair?

Select one or more of the following:

Explanation

Question 13 of 27

Fill the blank space to complete the text.

Surgical incisions in bone --> healing with minimal formation and minimal disruption to the bone's ordered structure

Explanation

Question 14 of 27

Neuronal cells are mitotic and can be replaced

Select one of the following:

Explanation

Question 15 of 27

What is Gliolisis?

Select one of the following:

Explanation

Question 16 of 27

In PNS (Peripheral nervous system), nerve axons can be ❌. If Basement membrane of ❌ is disrupted, resorbed axons may miss each other resulting in a traumatic ❌. If they are ❌, axonal growth has path to follow.

Drag and drop to complete the text.

Explanation

Question 17 of 27

When basement membrane is intact; (PNS)

Select one or more of the following:

Explanation

Question 18 of 27

Tissue healing in liver - acute injury heals by complete regeneration, whilst chronic is usually leading to collapse of reticulin framework, along with surrounding by fibrosis also known as CIRRHOSIS.

Select one of the following:

Explanation

Question 19 of 27

Which one of these are correct in regards to tissue healing in kidneys?

Select one or more of the following:

Explanation

Question 20 of 27

Metaplasia is a form of healing in epithelial surfaces

Bone repair depends on;
Type of ❌ - Result of strength & direction of applied force --> ❌ force (compressional fracture), Torsion force (❌ fracture), Combined ❌ and compressional force leads to an ❌ and displaced fracture
Adjacent tissue damage effects ❌ of repair. (e.g muscles)

Healing of bone phases
1:
2: Reparative
3:

In ( Remodelling, Inflammatory, Reparative ) phase (III) of bone repair, it may take years. Bone contours are re-organised and excess ( callus, scar tissue ) removed.

Respiratory epithelium ( can, cannot ) regenerate. However, basement membrane must be intact and CT framework minimally disrupted. If basement membrane disrupted, ( fibrosis, inflammation ) occurs.