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Cholinergic Drugs- Pharmacology 4th Year- PMU

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Cholinergic Drugs- Pharmacology 4th Year- PMU

Question 1 of 27

1

Point out the cholinergic neurons

Select one or more of the following:

preganglionic sympathetic
postganglionic sympathetic
preganglionic parasympathetic
postganglionic parasympathetic

Explanation

Question 2 of 27

1

Muscarinic cholinergic receptors are located in:

Select one or more of the following:

skeletal muscles
bronchial smooth muscles
heart
smooth muscles of GIT

Explanation

Question 3 of 27

1

Nicotinic cholinergic receptors are located in:

Select one or more of the following:

autonomic ganglia
adrenal gland medulla
heart muscle
skeletal muscles

Explanation

Question 4 of 27

1

Pharmacological effects of Acetylcholine are:

Select one or more of the following:

bradycardia
tachycardia
increased digestive (abundant saliva), bronchial, cutaneous, (sweat) and lacrimal secretions
increased tone and peristaltic contractions of GIT

Explanation

Question 5 of 27

1

M-receptor agonist used for treatment of glaucoma is:

Select one or more of the following:

Atropini sulfas
Pilocarpini hydrochloridum
Neostigmini methylsulfas
Galantamini bromidum

Explanation

Question 6 of 27

1

What are the effects of Pilocarpine after eye application?

Select one or more of the following:

mydriasis
miosis
increases the intraocular pressure
decreases the intraocular pressure

Explanation

Question 7 of 27

1

Clinical indications for prescribing N-receptor agonists are:

Select one or more of the following:

smoking cessation
atherosclerosis
premedication in anesthesia
muscle relaxation

Explanation

Question 8 of 27

1

Acetylcholine esterase inhibitors (anticholinesterases) are:

Select one or more of the following:

lpratropii bromidum
Galantamine bromidum
Neostigmine methylsulfas
Pyridostigmine bromidum

Explanation

Question 9 of 27

1

Indications for the clinical use of anticholinesterases are:

Select one or more of the following:

paralytic ileus
atropine intoxication
spastic bronchitis
as antidote of tubocurarine

Explanation

Question 10 of 27

1

Anticholinesterases are contraindicated in:

Select one or more of the following:

bronchial asthma
paralytic ileus
epilepsy
bradycardia

Explanation

Question 11 of 27

1

Point out the major features of the irreversible acetylcholine-esterase inhibitors:

Select one or more of the following:

They are organophosphate agents
Cause long-lasting elevation of acetylcholine levels
Their effect is antagonized by cholinolytic agents
Obidoxime is their specific antagonist

Explanation

Question 12 of 27

1

Symptoms of organophosphate intoxication can be treated with:

Select one or more of the following:

Acetylcholine
Atropine sulphas
Reactivators of acetylcholine esterase enzyme
Inhibitors of acetylcholine esterase

Explanation

Question 13 of 27

1

Antimuscarinic receptor antagonists are:

Select one or more of the following:

Atropini sulfas
Butylscopolamine
Atracurium besilas
Ipratropium bromidum

Explanation

Question 14 of 27

1

Synthetic antimuscarinic drugs are:

Select one or more of the following:

Pilocarpini hydrochloridum
Ipratropium bromidum
Butylscopolamine
Tiotropium bromidum

Explanation

Question 15 of 27

1

Pharmacological effects of antimuscarinic drugs are:

Select one or more of the following:

tachycardia
intestinal smooth muscle relaxation
mydriasis
decrease the secretion of exocrine glands

Explanation

Question 16 of 27

1

Clinical indications for prescribing antimuscarinic drugs are:

Select one or more of the following:

bronchial asthma
spasm of the smooth muscles of GlT
to elicit papillary dilation
glaucoma

Explanation

Question 17 of 27

1

Adverse drug reactions of Atropine are:

Select one or more of the following:

dry mouth
tachycardia
difficulties in seeing close objects
disorientation and hallucinations

Explanation

Question 18 of 27

1

Symptoms of intoxication with antimuscarinic agents are treated with:

Select one or more of the following:

Obidoxime
Anticholinesterases
Atropine sulphas
Acetylcholine

Explanation

Question 19 of 27

1

Non-depolarizing neuromuscular blockers paralyse the skeletal muscles in the following order:

Select one or more of the following:

head and neck, limbs, trunk, diaphragm and intercostal muscles
limbs, trunk, diaphragm and intercostal muscles, head and neck
diaphragm and intercostal muscles, head and neck, limbs
trunk, diaphragm and intercostal muscles, head and neck, limbs

Explanation

Question 20 of 27

1

Which of the following drugs are non-depolarising muscle blockers?

Select one or more of the following:

Atracurium besilas
Pancuronium bromidum
Suxamethonium chloridum
Tubocurarine hydrochloridum

Explanation

Question 21 of 27

1

Adverse drug reactions of non-depolarizing muscle relaxants are:

Select one or more of the following:

histamine release
hypotension
hypertension
allergic reaction

Explanation

Question 22 of 27

1

Drug interactions can occur in concomitant use Of peripheral-acting muscle relaxants and:

Select one or more of the following:

aminoglycoside antibiotics
calcium antagonists
halogen anaesthetics
cardiac glycosides

Explanation

Question 23 of 27

1

Which of the following drugs will antagonise the effect of the non-depolarizing neuromuscular blockers?

Select one or more of the following:

Anticholinesterases
MAO inhibitors
Antimuscarinic agents
Aminoglycoside antibiotics

Explanation

Question 24 of 27

1

What are the main features of Suxamethonium chioridum:

Select one or more of the following:

short-lasting effect
has no antagonist
anticholinesterases prolong its effect
oral administration

Explanation

Question 25 of 27

1

Adverse drug reactions of depolarizing muscle relaxants are-

Select one or more of the following:

tremor
arrhythmia
allergic reactions
prolonged neuromuscular blockade in people with plasma cholinesterase deficiency

Explanation

Question 26 of 27

1

Indications for treatment with central muscle relaxants are-

Select one or more of the following:

spasms of the skeletal muscles as a result of CNS damage
multiple sclerosis
surgery interventions
myasthenia gravis

Explanation

Question 27 of 27

1

Which of drugs are central acting muscle relaxants?

Select one or more of the following:

Tetrazepam
Tolperison
Bromocriptine
Baclofen

Explanation