Matthew Coulson
Quiz by , created more than 1 year ago

Genetics in Psychiatry lecture given by J Berg on 12/10/2018

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Matthew Coulson
Created by Matthew Coulson about 6 years ago
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Psychiatry Genetics

Question 1 of 12

1

By what mechanism is Huntington’s Disease inherited?

Select one of the following:

  • Autosomal Dominant

  • Autosomal Recessive

  • X-linked Recessive

  • X-linked Dominant

  • Multifactorial Inheritance

Explanation

Question 2 of 12

1

If your patient has an autosomal dominant condition, what are the chances that their child will get it?

Select one of the following:

  • 100%

  • 25%

  • 75%

  • 12.5%

  • 50%

Explanation

Question 3 of 12

1

In genetics, what name is given to the phenomenon whereby as a genetic disorder is passed on from generation to generation, the symptoms of the disorder become apparent at an earlier age with each generation?

Select one of the following:

  • Acceleration

  • Penetrance

  • Anticipation

  • Heritability

  • Transformation

Explanation

Question 4 of 12

1

Huntington's Disease patients tend to experience which of the following symptoms?

Select one of the following:

  • Chorea

  • Myoclonus

  • Tic

  • Tremor

Explanation

Question 5 of 12

1

Select from the dropdown list to complete the text.

Huntington's disease is caused genetically via repeats of a series of bases - ( CAG, CAT, TAT, TAG )

Explanation

Question 6 of 12

1

Select from the dropdown lists to complete the text.

The CAG repeats in Huntington's disease occur on the ( 1st, 2nd, 3rd, 10th ) exon encoding the poly-( glutamine, coronin, lactase, actin, salazine ) protein

Explanation

Question 7 of 12

1

Select from the dropdown list to complete the text.

When an individual has more than ( 38, 32, 48, 42 ) CAG repeats on the 1st exon encoding glutamine, they will develop Huntington's at some point in their life.

Explanation

Question 8 of 12

1

Select from the dropdown list to complete the text.

A normal human has less than ( 32, 38, 42, 28 ) CAG repeats on the 1st exon encoding poly-glutamine

Explanation

Question 9 of 12

1

The more CAG repeats that are present, the earlier in life the individual will develop Huntington's Disease

Select one of the following:

  • True
  • False

Explanation

Question 10 of 12

1

Which of these symptoms would be inconsistent with mania with psychotic symptoms?

Select one of the following:

  • Normal sleep pattern

  • Irritability instead of elation

  • Delusional idea that they are being monitored by the police

  • Physical aggression

  • Flight of ideas

Explanation

Question 11 of 12

1

Which of these can be a feature of hypomania?

Select one of the following:

  • Hearing a voice saying, “you are special”

  • Hearing a voice saying, “everyone is watching you”

  • Paranoid delusions

  • Impulsive overspending

  • Self-neglect causing dehydration

Explanation

Question 12 of 12

1

Bipolar I is a condition that affects roughly 1% of the British population. Is Bipolar I associated with mania or hypomania?

Select one of the following:

  • Mania

  • Hypomania

Explanation

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