Analgesia

Question 1 of 11

1

The WHO Analgesic ladder (least potent at top):
❌
❌
❌
❌

Drag and drop to complete the text.

Paracetamol

NSAID

Weak Opioid

Strong Opioid

Explanation

Question 2 of 11

1

Therefore, order the following drugs based on the analgesic ladder, with least potent at the top.
❌
❌
❌
❌

Drag and drop to complete the text.

Paracetamol

Ibuprofen

Codeine

Morphine

Explanation

Question 3 of 11

1

Therefore, order the following drugs based on the analgesic ladder, with least potent at the top.
❌
❌
❌
❌

Drag and drop to complete the text.

Paracetamol

Indomethacin

Tramadol

Oxycodone

Explanation

Question 4 of 11

1

Select from the dropdown lists to complete the text.

Opioids provide analgesia via inhibition of voltage gated ( Calcium, Potassium, Sodium ) channels and promotion of ( Potassium, Chlorine, Calcium, Sodium ) channel opening (to suppress excitation of projection neurons)

Explanation

Question 5 of 11

1

Opioid receptors are distributed throughout the nervous system and are traditionally arranged into three classes. Which class is responsible for most of the analgesic action of opioids?

Select one of the following:

μ (mu)
δ (delta)
κ (kappa)

Explanation

Question 6 of 11

1

Select from the dropdown list to complete the text.

Tramadol is a weak ( μ, κ, δ ) receptor agonist

Explanation

Question 7 of 11

1

Epileptic patients should not be given which of the following analgesics?

Select one of the following:

Tramadol
Methadone
Morphine
Codeine

Explanation

Question 8 of 11

1

Fill the blank space to complete the text.

Which analgesic is given to aid withdrawal symptoms from strong opioids such as heroin?

Explanation

Question 9 of 11

1

Fill the blank space to complete the text.

Patients who experience an overdose of a strong opioid can be reversed using a short acting μ-receptor antagonist called

Explanation

Question 10 of 11

1

The therapeutic benefit of NSAIDs largely comes via inhibition of which COX receptor?

Select one of the following:

COX1 Receptor
COX2 Receptor

Explanation

Question 11 of 11

1

Which of the following drugs would provide the highest level of analgesia in a patient experiencing neuropathic pain?

Select one of the following:

Gabapentin
Ibuprofen
Indomethacin
Paracetamol
Codeine

	Created by Matthew Coulson about 6 years ago

Analgesia lecture given by John Peters in Week 5. Lots of information but have only taken what are in my view the main learning points.

Analgesia

Question 1 of 11

The WHO Analgesic ladder (least potent at top): ❌ ❌ ❌ ❌

Drag and drop to complete the text.

Explanation

Question 2 of 11

Therefore, order the following drugs based on the analgesic ladder, with least potent at the top. ❌ ❌ ❌ ❌

Drag and drop to complete the text.

Explanation

Question 3 of 11

Therefore, order the following drugs based on the analgesic ladder, with least potent at the top. ❌ ❌ ❌ ❌

Drag and drop to complete the text.

Explanation

Question 4 of 11

Select from the dropdown lists to complete the text.

Opioids provide analgesia via inhibition of voltage gated Calcium Potassium Sodium( Calcium, Potassium, Sodium ) channels and promotion of Potassium Chlorine Calcium Sodium( Potassium, Chlorine, Calcium, Sodium ) channel opening (to suppress excitation of projection neurons)

Explanation

Question 5 of 11

Opioid receptors are distributed throughout the nervous system and are traditionally arranged into three classes. Which class is responsible for most of the analgesic action of opioids?

Select one of the following:

Explanation

Question 6 of 11

Select from the dropdown list to complete the text.

Tramadol is a weak μ κ δ( μ, κ, δ ) receptor agonist

Explanation

Question 7 of 11

Epileptic patients should not be given which of the following analgesics?

Select one of the following:

Explanation

Question 8 of 11

Fill the blank space to complete the text.

Which analgesic is given to aid withdrawal symptoms from strong opioids such as heroin?

Explanation

Question 9 of 11

Fill the blank space to complete the text.

Patients who experience an overdose of a strong opioid can be reversed using a short acting μ-receptor antagonist called

Explanation

Question 10 of 11

The therapeutic benefit of NSAIDs largely comes via inhibition of which COX receptor?

Select one of the following:

Explanation

Question 11 of 11

Which of the following drugs would provide the highest level of analgesia in a patient experiencing neuropathic pain?

Select one of the following:

Explanation

The WHO Analgesic ladder (least potent at top):
❌
❌
❌
❌

Therefore, order the following drugs based on the analgesic ladder, with least potent at the top.
❌
❌
❌
❌

Therefore, order the following drugs based on the analgesic ladder, with least potent at the top.
❌
❌
❌
❌

Opioids provide analgesia via inhibition of voltage gated ( Calcium, Potassium, Sodium ) channels and promotion of ( Potassium, Chlorine, Calcium, Sodium ) channel opening (to suppress excitation of projection neurons)

Tramadol is a weak ( μ, κ, δ ) receptor agonist