Gintarė
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Cell biology, second edition, shorter course

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Intracellular signaling

Question 1 of 8

1

Which of the following doesn't exist?

Select one of the following:

  • Phospholipase C gama

  • Protein kinase B

  • Protein kinase A

  • Phospholipase C alfa

  • phospoholipase C beta

Explanation

Question 2 of 8

1

Inositol trisphosphate-gated calcium channels are located in...

Select one of the following:

  • regulated exocytotic vesicles

  • the plasma membrane

  • the inner mitochondrial membrane

  • the smooth endoplasmic reticulum

  • all of the above

Explanation

Question 3 of 8

1

Which of the following statements is false?

Select one of the following:

  • appearance of PIP3 at the plasma membrane can activate a protein kinase

  • hydrolysis of GTP by Ras can activate a protein kinase

  • an increase of cytosolic cAMP concentration can activate a protein kinase

  • dimerization of growth factor receptors can activate a protein kinase

  • an increase of cytosolic calcium concentratiojn can activate a protein kinase

Explanation

Question 4 of 8

1

Which of the following is an enzyme, one of whose substrates is a nucleotide triphosphate?

Select one of the following:

  • Ras

  • The PDGF receptor

  • Protein kinase A

  • The insulin receptor

  • All of the above

Explanation

Question 5 of 8

1

Phosphotidylinositol bisphosphate is used in two different signaling pathways. these convert it, respectively into:

Select one of the following:

  • cAMP and c GMP

  • IP3 and PIP3

  • PIP2 and c AMP

  • IP3 and cAMP

  • PIP2 and PIP3

Explanation

Question 6 of 8

1

Arrival of a scent chemical at a scent-sensitive nerve cell causes that cell to

Select one of the following:

  • generate action poencials

  • open voltage-gated sodium channels in the plasma membrane

  • open cAMP-gated channels in the plasma membrane

  • activae adenylate cyclase

  • all of these above

Explanation

Question 7 of 8

1

Depolarization of axon terminals causes calcium ions to flow into the cytosol through

Select one of the following:

  • calcium ATPases

  • voltage - gated calcium channels

  • cAMP-gated calcium channels

  • inositol trisphosphate-gated calcium channels

  • ryanodine receptors

Explanation

Question 8 of 8

1

Why majority of transmitters are released from cells by exocytosis?

Select one of the following:

  • because different set of receptors activates Gs

  • Tyrosine kinases are Grb2 receptors

  • Because exocytosis is induced by an increase of cytosolic calcium concentration

Explanation

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