Christina Marshall
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Biology Quiz on Bio 110 Final: Chapter 14, created by Christina Marshall on 13/12/2017.

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Christina Marshall
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Bio 110 Final: Chapter 14

Question 1 of 10

1

A mutation removes a single base pair within the coding sequence of a gene and inactivates the protein encoded by the gene. Such a mutation is

Select one of the following:

  • A silent mutation

  • A missense mutation

  • A nonsense mutation

  • A frameshift mutation

  • Both b and c

Explanation

Question 2 of 10

1

Some point mutations lead to an mRNA that produces a shorter polypeptide. This type of mutation is known as a _________ mutation.

Select one of the following:

  • neutral

  • silent

  • missense

  • nonsense

  • chromosomal

Explanation

Question 3 of 10

1

In which location is a mutation least likely to affect gene function?

Select one of the following:

  • Promoter

  • Coding Region

  • Splice Junction

  • Intergenic Region

  • Regulatory site

Explanation

Question 4 of 10

1

Mutagens can cause mutations by

Select one of the following:

  • chemically altering DNA nucleotides

  • disrupting DNA replication

  • altering the genetic code of an organism

  • all of the above

  • a and b only

Explanation

Question 5 of 10

1

The mutagenic effect of UV light is

Select one of the following:

  • the alteration of cytosine bases and adenine bases

  • the formation of adenine dimers that interfere with genetic expression

  • the breaking of the sugar-phosphate backbone of the DNA molecule

  • the formation of thymine dimers that disrupt DNA replication

  • the deletion of thymine bases along the DNA molecule

Explanation

Question 6 of 10

1

The Ames test

Select one of the following:

  • provides a way to determine if any type of cell has experienced a mutation

  • provides a way to determine if an agent is a mutagen

  • allows researchers to experimentally disrupt gene activity by causing a mutation in a specific gene

  • provides a way to repair mutation in bacterial cells

  • does all the above

Explanation

Question 7 of 10

1

Xeroderma pigmentosum

Select one of the following:

  • is a genetic disorder that results in uncontrolled cell growth

  • is a genetic disorder in which the NER System is not fully functional

  • is a genetic disorder that results in the loss of pigment in certain patches of skin

  • results from the lack of DNA polymerase proofreading

  • Both b and d are true of this disorder.

Explanation

Question 8 of 10

1

If a mutation eliminated the function of UvrC, which aspect of nucleotide excision repair would not work?

Select one of the following:

  • Sensing a damaged DNA site

  • Endonuclease cleavage of the damaged strand

  • removal of the damaged strand

  • synthesis of a new strand, using the undamaged strand as a template

  • none of the above

Explanation

Question 9 of 10

1

Cancer cells are said to be metastatic when they

Select one of the following:

  • begin to divide uncontrollably

  • invade healthy tissue

  • migrate to other parts of the body

  • cause mutations in other healthy cells

  • do all of the above

Explanation

Question 10 of 10

1

Oncogenes can be produced by

Select one of the following:

  • missense mutations

  • gene amplification

  • chromosomal translocation

  • retroviral insertion

  • all of the above

Explanation

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