Quiz by Maddy Wallace, created more than 1 year ago

Medicine Quiz on Scarring (fibrosis), created by Maddy Wallace on 04/12/2017.

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	Created by Maddy Wallace over 6 years ago

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Scarring (fibrosis)

Question 1 of 4

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❌ --> ❌ --> ❌ --> ❌ --> migration of ❌ --> new ❌ --> ❌ --> scar matures

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clot

Bleed

acute inflammation

chronic inflammation

fibroblasts

platelets

calcium ions

results in angiogenesis and collagen

ECM

elastin

Explanation

Question 2 of 4

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Tissue ( remodelling, regeneration, renewal, proliferation ): the ECM of ( granulation, epithelial, vascular ) tissue must be degraded to ( remodel, redesign ) tissue in healing. Matrix metalloproteinases (MMPs) are ( enzymes, cytokines, growth factors, caspases ) that each break down one component of this ECM. They mediate long- term scar maturation and degradation, which is why they can look better over time. The action of MMPs is regulated by ( TIMPs, SIMPs, PIMPs, DIMPs ).

Explanation

Question 3 of 4

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Fibrotic tissue is ( weaker, stronger ) and ( less, more ) elastic than healthy tissue.

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Question 4 of 4

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Fibroblasts are connective tissue stem cells. ( Growth factors, Cytokines, Platelets, Histamines ) cause them to migrate and ( proliferate, differentiate, hallucinate, debate, situate ). They secrete ECM components, ( collagen, fibrinogen, platelets, lipids ) and elastin.

Explanation