Michael Jardine
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PHSI3012 12-1 Diabetes and its Medical Complications (T3L5)

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Michael Jardine
Created by Michael Jardine over 6 years ago
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PHSI3012 12-1 Diabetes and its Medical Complications (T3L5)

Question 1 of 8

3

Diabetes is diagnosed when:
- The fasting glucose level is (on 2 separate occasions);
- Glucose is 2 hours after a glucose drink (on 2 separate occasions);
- The HbA1c level is (on 2 separate occasions).
(HbA1c is glycosylated haemoglobin (occurs when Hb exposed to high glucose concentrations). It’s considered indicative of CHRONIC hyperglycaemia.

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    >7 mmol/L
    >7%
    >11 mmol/L
    >11%
    >6.5%
    >6.5 mmol/L

Explanation

Question 2 of 8

2

All 3 types of diabetes are increasing in prevalence (in Aus). They are:
Type 1 diabetes (accounting for of diabetes);
Type 2 diabetes (accounting for of diabetes);
Gestational diabetes (also increasing).

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    10%
    15%
    85%
    90%
    80%
    20%

Explanation

Question 3 of 8

2

Correlation of diabetes and obesity:
of diabetics are overweight; of overweight people have diabetes.

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    85%
    70%
    30%
    15%

Explanation

Question 4 of 8

3

The complications of diabetes can be both MACROVASCULAR and MICROVASCULAR. Which is each?
(put them in alphabetical order)
MACROVASCULAR: , , ;
MICROVASCULAR: , , .

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    Ischaemic heart disease
    Peripheral Vascular Disease
    Stroke
    Diabetic Nephropathy
    Diabetic Neuropathy
    Diabetic Retinopathy

Explanation

Question 5 of 8

1

Select from the dropdown list to complete the text.

The link between impaired glucose metabolism and microvascular pathophysiology (e.g. diabetic retinopathy) is through the ( Sorbitol, Sorbolene, Inositol, Inosolene ) pathway.
(in the presence of hyperglycaemia, aldose reductase catalyses the conversion of glucose into [above])

Explanation

Question 6 of 8

1

Select from the dropdown list to complete the text.

Hyperglycaemia ( Increases, Decreases ) the activity of the Polyol pathway (which involves Sorbitol).

Explanation

Question 7 of 8

2

Diabetic complications are common.
of people with diabetes will develop impaired vision due to retinopathy;
of people with diabetes will experience some form of neuropathy;
of people with diabetes will develop symptoms of nephropathy (most of whom will go on to end-stage renal disease).

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    50%
    60-70%
    20-30%

Explanation

Question 8 of 8

1

AGE = ??

Select one of the following:

  • Advanced Glycation Endproducts

  • Advanced Glycosylation Endproducts

  • Advanced Glycation Enzymes

  • Advanced Glycosylation Enzymes

Explanation