Michael Jardine
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PHSI3012 11-1 Pathogenesis of Obesity (T3L3)

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Michael Jardine
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PHSI3012 11-1 Pathogenesis of Obesity (T3L3)

Question 1 of 15

1

In 2011, 62.8% of Australians over 18yo were __________.

Select one of the following:

  • Obese

  • Overweight

  • Obese OR Overweight

  • [none of the above]

Explanation

Question 2 of 15

3

Which of the following can go along with obesity?

Select one or more of the following:

  • Cardiovascular disease

  • Cancer

  • Insulin resistance

  • Sleep apnoea

  • Asthma

  • Alzheimer’s

  • T2D

  • Infertility

  • Anorexia

  • T1D

Explanation

Question 3 of 15

1

Select from the dropdown list to complete the text.

The average energy expenditure is roughly ( 1,000, 2,500, 6,000, 20,000 ) kcal/day.

Explanation

Question 4 of 15

1

Does Ghrelin stimulate or suppress hunger/feeding?

Select one of the following:

  • Stimulate

  • Suppress

Explanation

Question 5 of 15

1

Does Peptide YY (PYY) induce hunger or satiety?

Select one of the following:

  • Satiety

  • Hunger

Explanation

Question 6 of 15

1

Select from the dropdown list to complete the text.

Leptin downregulates the production of appetite-( -stimulating, -suppressing ) neuropeptides.

Explanation

Question 7 of 15

1

Does Insulin push you towards hunger or satiety?

Select one of the following:

  • Satiety

  • Hunger

Explanation

Question 8 of 15

1

Environmental- vs Genetic- determinants of obesity.
accounts for ~30-40%;
accounts for ~60-70%.

Select option below to complete the highlighted text

    Genetics
    Environment

Explanation

Question 9 of 15

1

Adoption studies suggest a stronger role for than in predicting future weight.

Select option below to complete the highlighted text

    Genetics
    Environment

Explanation

Question 10 of 15

1

Which of the following two single-gene-defects could cause Rapid weight gain, Hyperplasia?

Select one or more of the following:

  • Leptin (LEP)

  • Leptin receptor (LEPR)

  • MelanoCortin-4 Receptor (MC4R)

Explanation

Question 11 of 15

1

Which of the following is the most common single-gene cause of obesity? (it’s only present in 2-5% of persons with severe obesity, though!)

Select one of the following:

  • MelanoCortin-4 Receptor (MC4R)

  • Leptin (LEP)

  • Leptin receptor (LEPR)

Explanation

Question 12 of 15

1

There are shitloads of genes associated with obesity. Broadly 4 categories (Monogenic oligogenic; Fat distribution-related; BMI-related genes; Overweight, Obesity-related). Treating them as a Venn diagram, what’s the only one in the overlap of all 4?

Select one of the following:

  • MC4R

  • LEPR

  • TUB

  • LEP

Explanation

Question 13 of 15

1

Select from the dropdown list to complete the text.

Gastric banding results in a mean weight reduction of ( 15-20%, ~25%, ~30% ) at 1 year.

Explanation

Question 14 of 15

1

Vertical-sleeve Gastrectomy results in what mean % weight reduction at 1 year?

Select one of the following:

  • 15-20%

  • ~25%

  • ~30%

Explanation

Question 15 of 15

1

Roux-en-Y Gastric Bypass (RNY) results in what mean % weight reduction at 1 year?

Select one of the following:

  • 15-20%

  • ~25%

  • ~30%

Explanation

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